From Chapter 1:
Perhaps the most likely scene of Raleigh's first experiments in the art of smoking was Durham House, which stood where the Adelphi Terrace and the streets between it and the Strand now stand. This was in the occupation of Sir Walter for twenty years (1583-1603), and he was probably resident there when Hariot returned from Virginia to make his report and instruct his employer in the management of a pipe. Walter Thornbury, in his "Haunted London," referring to the story of the servant throwing the ale over his smoking master, says: "There is a doubtful old legend about Raleigh's first pipe, the scene of which may be not unfairly laid at Durham House, where Raleigh lived." The ale story is mythical, but it is highly probable that Sir Walter's first pipes were smoked in Durham House. Dr. Brushfield quotes Hepworth Dixon, in "Her Majesty's Tower," as drawing "an imaginary and yet probable picture of him and his companions at a window of this very house, overlooking the 'silent highway':

From Chapter 8:
All's well that ends well; but one cannot help wondering what kind of tobacco it was that the Birmingham tradesman used, a half pipeful of which had such a deadly effect—but perhaps the effect was due to the salt, not to the tobacco.
In the year after that which witnessed Coleridge's adventure, i.e. in 1796, a tobacco-box with a history was the subject of a legal decision. This box, made of common horn and small enough to be carried in the pocket, was bought for fourpence by an overseer of the poor in the time of Queen Anne, and was presented by him in 1713 to the Society of Past Overseers of the parish of St. Margaret, Westminster. In 1720 the Society, in memory of the donor, ornamented the lid with a silver rim; and at intervals thereafter additions were made to an extraordinary extent to the box and its casings. Hogarth engraved within the lid in 1746 a bust of the victor of Culloden. Gradually the horn box was enshrined within one case after another—usually silver lined with velvet—each case bearing inscribed plates commemorating persons or events. A Past Overseer who detained the box in 1793 had to give it back after three years of litigation. A case of octagon shape records the triumph of Justice, and Lord Chancellor Loughborough pronouncing his decree for the restitution of the box on March 5, 1796. In later days many and various additions have been made to the many coverings of the box, recording public events of interest.