From Chapter 2:
Sir Francis Vere, in the account of his services by sea and land which he wrote about 1606, mentions that on an expedition to the Azores in 1597, the Earl of Essex, waiting for news of the enemy at St. Michael, "called for tobacco ... and so on horseback, with those Noblemen and Gentlemen on foot beside him, took tobacco, whilst I was telling his Lordship of the men I had sent forth, and orders I had given." Presently came the sound of guns, which "made his Lordship cast his pipe from him, and listen to the shooting."

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."