From Chapter 2:
A curious scene took place at Oxford in 1605 when King James visited the University. Two subjects were debated by learned dons before his Majesty, and one of them, at his own suggestion, was, "Whether the frequent use of tobacco is good for healthy men?" Among those who spoke were Doctors Ailworth, Gwyn, Gifford and Cheynell. The discussion, needless to say, being conducted in the presence of the author of the "Counterblaste to Tobacco," was not favourable to the herb. The King summed up in a speech which hopelessly begged the question while it contained plenty of strong denunciation. After his Majesty had spoken, one learned doctor, Cheynell, who is described by the recorder, Isaac Wake, the Public Orator of the University, as second to none of the doctors, had the courage to rise and, with a pipe held forth in his hand, to speak both wittily and eloquently in favour of tobacco from the medicinal point of view, praising it to the skies, says Wake, as of virtue beyond all other remedial agents. His wit pleased both the King and the whole assembly, whom it moved to laughter; but when he had finished, his Majesty made a lengthy rejoinder in which he said some curious things. He objected to the medicinal use of tobacco, and quite agreed with previous speakers that such a use must have arisen among Barbarians and Indians, who he went on to say had as much knowledge of medicine as they had of civilized customs. If, he argued, there were men whose bodies were benefited by tobacco-smoke, this did not so much redound to the credit of tobacco, as it did reflect upon the depraved condition of such men, that their bodies should have sunk to the level of those of Barbarians so as to be affected by remedies such as were effective on the bodies of Barbarians and Indians! His Majesty kindly suggested that doctors who believed in tobacco as a remedial agent should take themselves and their medicine of pollution off to join the Indians.

From Chapter 6:
There was indeed no diminution of tobacco-smoke in the coffee-houses. A visitor from abroad, Mr. Muralt, a Swiss gentleman, writing about 1696, said that character could be well studied at the coffee-houses. He was probably not a smoker himself, for he goes on to say that in other respects the coffee-houses are "loathsome, full of smoke like a guardroom, and as much crowded." He further observed that it was common to see the clergy of London in coffee-houses and even in taverns, with pipes in their mouths. A native witness of about the same date, Ned Ward, writes sneeringly in his "London Spy," 1699, of the interior of the coffee-house. He saw "some going, some coming, some scribbling, some talking, some drinking, some smoking, others jingling; and the whole room stinking of tobacco, like a Dutch scoot, or a boatswain's cabin.... We each of us stuck in our mouths a pipe of sotweed, and now began to look about us." Ward's contemporary, Tom Brown, took a different tone: he wrote of "Tobacco, Cole and the Protestant Religion, the three great blessings of life!"—as strange a jumble as one could wish for.